Either a placebo twice daily or the curcumin supplement theracurmin containing 90 mg of curcumin.
Theracurmin containing 90 mg of curcumin.
Attention was assessed as a secondary outcome.
Individuals were asked not to consume curcumin containing food for more than 7 days prior to the study.
The experimental group took theracurmin containing 90 mg of curcumin twice a day ie 180 mg curcumin day for 18 months.
The experimental group took theracurmin containing 90 mg of curcumin twice daily i e 180 mg curcumin day for 18 months.
The intervention is twice daily dosage of theracurmin 90 mg capsules.
This same dose was used in a successful trial of patients with mild cognitive impairment.
Theracurmin hp capsules containing 90 mg curcumin each that will be taken as one capsule twice daily for 6 months.
30 mg providing a controlled surface the colloidal dispersion 30 mg of curcumin turmeric root extract daily value not established other ingredients.
The investigators expect that the volunteers receiving the curcumin supplement will show less evidence of decline after 18 months than those receiving the placebo.
6 capsules equivalent to 180 mg curcumin.
Theracurmin is a novel preparation of turmeric that utilizes patented colloidal dispersion technology to enhance bioavailability and dramatically increase curcumin levels in the blood unlike other forms of curcumin theracurmin is water dispersible meaning it dissolves quickly and maintains solubility over time thereby improving curcumin s overall absorption.
1 capsule equivalent to 260 mg.
Blood samples were collected at regular intervals.
The following tests were used to assess cognitive performance.
Forty subjects age 51 84 years were randomized to a bioavailable form of curcumin theracurmin containing 90 mg of curcumin twice daily n 21 or placebo n 19 for 18 months.
Cognitive performance was assessed through verbal and visual testing.
Primary outcomes were verbal buschke selective reminding test srt and visual brief visual memory test revised bvmt r memory and attention trail making a was a secondary outcome.
Verbal performance buschke selective reminding test srt visual performance brief visual memory test revised bvmt r.
Subjects will be randomly assigned to one of two treatment groups.
The dosage of curcumin from each supplement type was not equal.